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一项关于抗垂体血清的研究。

A study on anti-pituitary serum.

作者信息

Pierpaoli W, Sorkin E

出版信息

Immunology. 1969 Mar;16(3):311-8.

PMID:4890311
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1409622/
Abstract

Rabbit anti-mouse pituitary serum was prepared. Its affinity for the acidophilic, growth hormone producing cells was demonstrated by the fluorescent antibody technique. The anti-pituitary serum also had some anti-growth hormone activity. Besides the changes described earlier in the thymus and lymphoid tissue injection of anti-pituitary serum into young mice also produced an alteration in the thyroid gland.

摘要

制备了兔抗小鼠垂体血清。通过荧光抗体技术证明了其对嗜酸性、产生生长激素的细胞的亲和力。抗垂体血清也具有一些抗生长激素活性。除了前面描述的胸腺和淋巴组织的变化外，向幼鼠注射抗垂体血清还会引起甲状腺的改变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b37/1409622/935df543ba19/immunology00386-0027-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b37/1409622/1cb178a992ba/immunology00386-0026-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b37/1409622/935df543ba19/immunology00386-0027-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b37/1409622/1cb178a992ba/immunology00386-0026-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b37/1409622/935df543ba19/immunology00386-0027-a.jpg

相似文献

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Immunology. 1969 Mar;16(3):311-8.
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引用本文的文献

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Immunological blockade of the adenohypophysis and its possible application in prophylaxis and therapy of neoplasia.腺垂体的免疫阻断及其在肿瘤预防和治疗中的可能应用。
Experientia. 1972 Mar 15;28(3):336-9. doi: 10.1007/BF01928725.
2
The effect of hypophysectomy on the immune response.垂体切除术对免疫反应的影响。
Immunology. 1970 May;18(5):671-9.
3
Specificity and properties of anti-adenohypophysis serum. I. Mode of preparation, titration and effects of neonatal injection into rats.抗腺垂体血清的特异性及特性。I. 制备方法、滴定及对新生大鼠注射的影响

本文引用的文献

1
ORGAN-SPECIFIC ANTIGENS OF LIVER, TESTICLE AND PITUITARY.肝脏、睾丸和垂体的器官特异性抗原。
J Immunol. 1965 Jan;94:157-63.
2
SEROLOGICAL STUDIES ON RABBIT ANTIBODIES TO THE RABBIT ANTERIOR PITUITARY.兔抗兔垂体前叶抗体的血清学研究
Immunology. 1964 Mar;7(2):172-81.
3
Inhibitory effects of antirat pituitary serum (APS) on hypophysectomized rats injected with pituitary hormones.抗大鼠垂体血清（APS）对注射垂体激素的垂体切除大鼠的抑制作用。
Clin Exp Immunol. 1972 Jul;11(3):427-39.
4
Hormones, thymus and lymphocyte functions.激素、胸腺与淋巴细胞功能。
Experientia. 1972 Nov 15;28(11):1385-9. doi: 10.1007/BF01965362.
5
Serum immunoglobulin levels in thymus-deficient pituitary dwarf mice.胸腺缺陷型垂体性侏儒小鼠的血清免疫球蛋白水平
Immunology. 1970 Mar;18(3):437-41.
6
Possible association of thymus dysfunction with fading syndromes in puppies and kittens.幼犬和幼猫胸腺功能障碍与消瘦综合征之间可能存在的关联。
Vet Clin North Am Small Anim Pract. 1987 May;17(3):603-16. doi: 10.1016/s0195-5616(87)50056-0.
7
Interdependence of thymic and neuroendocrine functions in ontogeny.个体发育过程中胸腺与神经内分泌功能的相互依存关系。
Clin Exp Immunol. 1976 Jun;24(3):501-6.
Acta Endocrinol (Copenh). 1960 Sep;35:139-60. doi: 10.1530/acta.0.xxxv0139.
4
Adaptation of the antiglobulin test for use with tannic acid treated erythrocytes.抗球蛋白试验用于经鞣酸处理红细胞的适应性研究。
J Immunol. 1959 Apr;82(4):279-89.
5
Hormones and immunological capacity. II. Reconstitution of antibody production in hormonally deficient mice by somatotropic hormone, thyrotropic hormone and thyroxin.激素与免疫能力。II. 生长激素、促甲状腺激素和甲状腺素对激素缺乏小鼠抗体产生的重建作用。
Immunology. 1969 Feb;16(2):217-30.