Jin Y P, Song Q C, Wu H
2nd Affiliated Hospital of Human Medical University, Changsha.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1992 Aug;12(8):461-4, 451-2.
The erythroid colony formating ability and the therapeutic efficacy were investigated in patients with chronic renal failure (CRF) before and after treatment with baoyuantang. The results showed that the number of CFU-E, BFU-E of bone marrow was found lower in CRF patients than that in normal controls, and there was inhibitory action in the CRF serum on the number of CFU-E, BFU-E of normal human bone marrow. After treatment with baoyuantang, the amount of Hb was increased and creatinine decreased in CRF patients, and its effective rate reached 83.3%. The above-mentioned inhibitory action in CRF serum was also reduced post-treatment. The results indicated that baoyuantang could increase the ability for proliferation and differentiation of erythroid progenitor and adjust anemia in CRF patient.
观察了保元汤治疗慢性肾功能衰竭（CRF）患者前后的红细胞集落形成能力及治疗效果。结果显示，CRF患者骨髓CFU-E、BFU-E数量低于正常对照，CRF血清对正常人骨髓CFU-E、BFU-E数量有抑制作用。保元汤治疗后，CRF患者Hb升高，肌酐降低，有效率达83.3%。治疗后CRF血清上述抑制作用也降低。结果表明，保元汤可提高CRF患者红系祖细胞的增殖分化能力并改善贫血。
