Mayumi M
Department of Pediatrics, Kyoto University Hospital, Japan.
Leuk Lymphoma. 1992 Jun;7(3):243-50. doi: 10.3109/10428199209053629.
EoL-1 cells, a recently established human eosinophilic leukemia cell line, have cytological features of myeloblasts under normal culture conditions, and differentiate not only phenotypically but also functionally into eosinophils by a number of stimuli. EoL-1 cells are particularly useful for analyzing leukemic cell differentiation and the properties of malignant eosinophils. EoL-1 cells are also a useful in vitro model for studying human eosinophil functions and their regulation.
EoL-1细胞是一种最近建立的人类嗜酸性粒细胞白血病细胞系，在正常培养条件下具有成髓细胞的细胞学特征，并且通过多种刺激不仅在表型上而且在功能上分化为嗜酸性粒细胞。EoL-1细胞对于分析白血病细胞分化和恶性嗜酸性粒细胞的特性特别有用。EoL-1细胞也是研究人类嗜酸性粒细胞功能及其调节的一种有用的体外模型。
