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新生大鼠皮质和海马电活动中的年龄变体和年龄不变节律

Age-variant and age-invariant rhythmicities in the cortical and hippocampal electrical activities of neonatal rats.

作者信息

Dux M, Rubicsek G, Wolff J, Joó F, Benedek G

机构信息

Department of Physiology, Albert Szent-Györgyi Medical University, Szeged, Hungary.

出版信息

Chronobiologia. 1992 Jul-Dec;19(3-4):163-73.

PMID:1478115
Abstract

The neocortical and hippocampal electrical activities were studied in 8, 15, 22, and 29-day-old rats. Segments of EEG recorded for 4 hours were analyzed by means of fast Fourier transformation. The sleep-wake activity stages were determined. The developments in the neocortical and hippocampal EEG activities were characterized by the gradual appearance of adult-like EEG waves and a shift towards higher frequencies in the theta wave range of the hippocampal electrical activity. The power value in the theta range, however, exhibited age-invariant rhythmicities with cycle lengths of about 9.5-11 and 16-22 min. The manifestation of such an age-invariant rhythm can be interpreted as an electrical manifestation of the rest-activity cycle originally described by KLEITMAN25.

摘要

对8日龄、15日龄、22日龄和29日龄的大鼠进行了新皮质和海马体电活动研究。通过快速傅里叶变换分析记录4小时的脑电图片段。确定睡眠-觉醒活动阶段。新皮质和海马体脑电图活动的发展特点是逐渐出现类似成年大鼠的脑电波,海马体电活动的θ波范围向更高频率转变。然而,θ波范围内的功率值表现出年龄不变的节律性,周期长度约为9.5 - 11分钟和16 - 22分钟。这种年龄不变节律的表现可解释为最初由克莱特曼描述的静息-活动周期的电表现。

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