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产前肾脏异常的检测。

Antenatal detection of renal abnormalities.

作者信息

Ashe R G, Campbell N, Dornan J C

机构信息

Royal Maternity Hospital, Belfast, Northern Ireland.

出版信息

Ir J Med Sci. 1992 Nov;161(11):626-9. doi: 10.1007/BF02983768.

Abstract

The aim of this retrospective study is to assess the value of routine ultrasonography in the detection of renal abnormalities. Twenty-nine pregnancies (one set of twins) with suspected renal abnormalities (i.e. renal cystic spaces, oligohydramnios or hyperechoic kidneys) were delivered over a two year period (1.8.1987-31-7-1989) in a unit where 90% of pregnancies (6,562) were scanned routinely at 18-20 weeks gestation or later, if booking for confinement was delayed. In pregnancies with suspected anomalies prenatal ultrasound was performed monthly until 28 weeks and fortnightly until delivery. Non survivors [5] had histological or postmortem examination. Liveborn infants [25] had renal ultrasonography in the neonatal period and paediatric follow-up if abnormal. Sixteen (53%) of the 30 cases (one set of twins) suspected of renal abnormalities by routine prenatal ultrasonography had renal anomalies confirmed postnatally. Five women were non survivors, all of which had associated anomalies. In the eleven survivors the diagnoses were pelvi-ureteric junction obstruction [6], renal dysplasia [2], vesicoureteric reflux [2] and suspected ureterocele [1]. Fourteen infants with pelvicalyceal dilatation had normal postnatal renal ultrasound. Although abnormal prenatal renal ultrasound is a useful indicator of postnatal disease and aids decisions on the management of pregnancy, further large collaborative studies with extended paediatric follow-up are required to assess the significance of pelvicalyceal dilatation.

摘要

本回顾性研究的目的是评估常规超声检查在检测肾脏异常方面的价值。在两年期间(1987年8月1日至1989年7月31日),在一个单位中有29例(其中1例为双胞胎)疑似肾脏异常(即肾囊性间隙、羊水过少或高回声肾)的孕妇分娩,该单位90%的孕妇(6562例)在妊娠18 - 20周或之后(如果预定分娩时间延迟)进行常规扫描。对于疑似异常的孕妇,产前超声检查每月进行一次直至28周,之后每两周进行一次直至分娩。非存活者[5例]进行了组织学检查或尸检。存活婴儿[25例]在新生儿期进行了肾脏超声检查,若结果异常则进行儿科随访。在30例(1例双胞胎)通过常规产前超声检查疑似肾脏异常病例中,16例(53%)出生后肾脏异常得到证实。5名女性为非存活者,均伴有其他异常。在11名存活者中,诊断结果为肾盂输尿管连接部梗阻[6例]、肾发育不良[2例]、膀胱输尿管反流[2例]以及疑似输尿管囊肿[1例]。14例肾盂肾盏扩张的婴儿出生后肾脏超声检查结果正常。尽管产前肾脏超声异常是出生后疾病的有用指标,并有助于妊娠管理决策,但仍需要进一步开展大型协作研究并延长儿科随访时间来评估肾盂肾盏扩张的意义。

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