Barratt C L, McLeod I D, Dunphy B C, Cooke I D
University Department of Obstetrics and Gynaecology, Jessop Hospital for Women, Sheffield, UK.
Hum Reprod. 1992 Oct;7(9):1240-4. doi: 10.1093/oxfordjournals.humrep.a137834.
The clinical value of two inexpensive and easy to perform sperm function tests (hypo-osmotic swelling and bovine sperm mucus penetration tests) were examined in a prospective study of in-vivo conception rates in 325 couples. Both tests were of no significant value alone or in combination with traditional semen characteristics in predicting pregnancy outcome. The two most predictive factors of conception were the length of infertility and percentage of progressively motile spermatozoa. Our data support the further investigation of sperm function using more sophisticated quantitative tests, specifically the examination of sperm motility.
在一项针对325对夫妇体内受孕率的前瞻性研究中,对两种廉价且易于操作的精子功能测试(低渗肿胀试验和牛精子黏液穿透试验)的临床价值进行了检验。单独使用这两种测试,或与传统精液特征相结合,在预测妊娠结局方面均无显著价值。受孕的两个最具预测性的因素是不孕时间长短和进行性运动精子的百分比。我们的数据支持使用更复杂的定量测试进一步研究精子功能,特别是对精子活力的检测。