Leznoff A, Binkley K E, Joffee R T, Levitt A, Richter M A
Department of Medicine, St. Michael's Hospital, University of Toronto, Ontario, Canada.
J Clin Psychopharmacol. 1992 Oct;12(5):355-7.
Four patients treated with fluoxetine alone developed generalized urticaria. One also suffered polyarthritis. These reactions subsided when fluoxetine was stopped. After 6-12 months, because of progressive psychiatric problems, fluoxetine was reintroduced using a desensitization protocol. In each case this was well tolerated, and fluoxetine has been continued without adverse affects for 3-10 months.