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木村病与嗜酸性粒细胞增多性血管淋巴样增生症:临床及组织病理学差异

Kimura's disease and angiolymphoid hyperplasia with eosinophilia: clinical and histopathologic differences.

作者信息

Chun S I, Ji H G

机构信息

Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea.

出版信息

J Am Acad Dermatol. 1992 Dec;27(6 Pt 1):954-8. doi: 10.1016/0190-9622(92)70293-o.

Abstract

BACKGROUND

There has been considerable controversy about the relation between Kimura's disease and angiolymphoid hyperplasia with eosinophilia (ALHE).

OBJECTIVE

We describe the clinical and histopathologic differences between the two diseases.

METHODS

We reviewed clinical findings and histopathologic changes in two cases of Kimura's disease and three cases of ALHE.

RESULTS

Kimura's disease shows typical lymphoid follicles. It is associated with lymphadenopathy and is always accompanied by peripheral eosinophilia. ALHE shows typical changes in endothelial cells. It is characterized by superficial papules or nodules with no lymphadenopathy and is less frequently accompanied by peripheral eosinophilia.

CONCLUSION

Kimura's disease and ALHE are separate entities.

摘要

背景

木村病与嗜酸性粒细胞增多性血管淋巴样增生症(ALHE)之间的关系一直存在很大争议。

目的

我们描述这两种疾病的临床和组织病理学差异。

方法

我们回顾了2例木村病和3例ALHE的临床发现和组织病理学变化。

结果

木村病表现出典型的淋巴滤泡。它与淋巴结病相关,且总是伴有外周血嗜酸性粒细胞增多。ALHE表现出内皮细胞的典型变化。其特征为浅表丘疹或结节,无淋巴结病,外周血嗜酸性粒细胞增多的情况较少见。

结论

木村病和ALHE是不同的疾病实体。

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