Brahs Allyson, Sledge Brigitte, Mullen Heidi, Newman Andrew, Mengesha Yebabe, Estrada Sarah
Ms. Brahs is with Western University of Health Sciences, College of Osteopathic Medicine of the Pacific in Pomona, California.
Drs. Sledge, Mullen, Newman, Mengesha, and Estrada are with HonorHealth Scottsdale Dermatology Residency Program and Affiliated Dermatology in Scottsdale, Arizona.
J Clin Aesthet Dermatol. 2021 Jun;14(6):49-54. Epub 2021 Jun 1.
Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon, benign inflammatory vasoproliferation. The literature is divided regarding whether it embodies a vascular neoplasm or a reactive process secondary to various stimuli. ALHE presents as solitary or clustered papules or nodules primarily on the head and neck, especially on or around the auricle. Histologically, ALHE is characterized by a proliferation of blood vessels lined by plump epithelioid endothelial cells and a prominent perivascular infiltrate rich in lymphocytes and eosinophils. ALHE follows a benign clinical course, yet treatment is challenging because of its high recurrence rate. We present the case of a 37-year-old Filipino man with lesions located on the central face. Kimura disease was considered due to his age, sex, and ethnicity; however, his clinical features-specifically, the presence of discrete papules and lack of lymphadenopathy-and his histological findings were consistent with ALHE. He reported trauma prior to the onset of the lesions, suggesting a reactive etiology.
嗜酸性粒细胞增多性血管淋巴样增生（ALHE）是一种罕见的良性炎症性血管增生。关于它是一种血管肿瘤还是继发于各种刺激的反应性过程，文献观点不一。ALHE主要表现为孤立或成簇的丘疹或结节，主要位于头颈部，尤其是耳廓上或其周围。组织学上，ALHE的特征是由丰满的上皮样内皮细胞衬里的血管增生以及富含淋巴细胞和嗜酸性粒细胞的显著血管周围浸润。ALHE临床过程良性，但由于其高复发率，治疗具有挑战性。我们报告了一例37岁菲律宾男性，其病变位于面部中央。考虑到患者的年龄、性别和种族，曾怀疑为木村病；然而，他的临床特征——特别是存在离散丘疹且无淋巴结病——以及组织学表现与ALHE一致。他报告病变出现前有外伤史，提示为反应性病因。
