麻风病和糖尿病患者足底溃疡的愈合率。

Healing rates of plantar ulcers in leprosy and diabetes.

作者信息

Birke J A, Novick A, Patout C A, Coleman W C

机构信息

Gillis W Long Hansen's Disease Center, Carville, LA 70721.

出版信息

Lepr Rev. 1992 Dec;63(4):365-74. doi: 10.5935/0305-7518.19920044.

DOI:10.5935/0305-7518.19920044

PMID:1479877

Abstract

Comparison was made of wound healing time in a consecutive series of leprosy and diabetic patients with plantar ulceration. In the leprosy group, 66 of 70 (94%) ulcers healed in a mean time of 42.7 (+/- 36.1) days, and in the diabetic group, 75 of 80 (94%) ulcers healed in a mean time of 39.7 (+/- 32.1) days. Analysis of all healed ulcers using a general linear model found wound depth (p < 0.03), and wound diameter (p < 0.05) significantly related to ulcer healing time. Diagnosis, healing devices (cast, splint and cut-out sandal), age and sex were not significant. In diabetic subjects a regression model including depth, diameter and age explained 36% of the variation in healing time. A meaningful regression model was not found in leprosy patients.

摘要

对一系列连续性的患有足底溃疡的麻风病患者和糖尿病患者的伤口愈合时间进行了比较。在麻风病组中，70例溃疡中有66例（94%）愈合，平均愈合时间为42.7（±36.1）天；在糖尿病组中，80例溃疡中有75例（94%）愈合，平均愈合时间为39.7（±32.1）天。使用一般线性模型对所有愈合的溃疡进行分析发现，伤口深度（p<0.03）和伤口直径（p<0.05）与溃疡愈合时间显著相关。诊断、愈合器具（石膏、夹板和镂空凉鞋）、年龄和性别无显著相关性。在糖尿病患者中，一个包含深度、直径和年龄的回归模型解释了愈合时间变化的36%。在麻风病患者中未发现有意义的回归模型。