Neutra R R, Ostro B
Special Epidemiological Studies Program, California Department of Health Services, Berkley 94704.
Sci Total Environ. 1992 Dec 15;127(1-2):91-122; discussion 122-35. doi: 10.1016/0048-9697(92)90472-5.
Six members of the International Society for Environmental Epidemiology provide a discussion of the presentations of the authors of six studies dealing with the potential chronic disease side effects of water disinfection. This symposium, which was jointly sponsored by the Society and the United States Environmental Protection Agency (EPA) also involved state epidemiologists and engineers from state drinking water programs. This article summarizes the results of the studies and the comments about them. There was a general consensus that the recent EPA sponsored studies of cancer endpoints have strengthened the evidence linking bladder cancer with long term exposure to chlorinated drinking water. The evidence for links with colon cancer is not convincing and that for serum lipid changes is quite weak. Any risks, if real, are low when compared to the risk of infection from not disinfecting water. This is particularly true for small water systems where chlorination may be the only practical option.
国际环境流行病学学会的六位成员对六项研究的作者所做报告进行了讨论,这些研究探讨了水消毒可能产生的慢性病副作用。本次研讨会由该学会与美国环境保护局(EPA)联合主办,还邀请了州流行病学家以及来自州饮用水项目的工程师。本文总结了这些研究的结果以及相关评论。人们普遍认为,美国环境保护局近期资助的关于癌症终点的研究强化了膀胱癌与长期饮用氯化饮用水之间存在关联的证据。与结肠癌存在关联的证据并不令人信服,而与血清脂质变化相关的证据则相当薄弱。与未对水进行消毒而导致感染的风险相比,任何风险(如果确实存在的话)都很低。对于小型供水系统而言尤其如此,在这些系统中氯化消毒可能是唯一可行的选择。