Heinritzi K, Hartel I, Bollwahn W
II. Medizinischen Tierklinik Ludwig-Maximilians-Universität München.
Tierarztl Prax. 1992 Dec;20(6):595-9.
The immersible culture medium MICUR-BT used in human medicine for the detection of antimicrobial substances in the urine was tested for its suitability in pigs. In in-vitro tests, 15 pure antibiotic substances, 2 pure substance mixtures as well as 5 veterinary injection preparations with no direct antimicrobial effect were checked. The agar perforation test was used as a reference procedure. In a total of 65 pigs the detectability of 9 pure antibiotic and chemotherapeutic agents, 2 pure substance mixtures as well as 5 veterinary drugs with no direct antimicrobial effect was tested after oral or parenteral application. In the in-vivo tests the MICUR-BT test turned out to be more reliable than the agar perforation test. In 76.9% of the untreated pigs below 30 kg b.w. the MICUR-BT-test showed an antimicrobial effect. Such effects were reduced by 38.3% in the reference procedure.
用于人类医学尿液中抗菌物质检测的可浸没培养基MICUR - BT，针对其在猪身上的适用性进行了测试。在体外试验中，对15种纯抗生素物质、2种纯物质混合物以及5种无直接抗菌作用的兽用注射制剂进行了检查。琼脂打孔试验用作参考程序。在总共65头猪中，对9种纯抗生素和化疗药物、2种纯物质混合物以及5种无直接抗菌作用的兽药在口服或注射给药后进行了检测。在体内试验中，MICUR - BT试验比琼脂打孔试验更可靠。在体重低于30千克的未治疗猪中，76.9%的猪MICUR - BT试验显示有抗菌效果。在参考程序中，这种效果降低了38.3%。
