Ansorg R
Dtsch Med Wochenschr. 1984 Mar 30;109(13):488-91. doi: 10.1055/s-2008-1069219.
The actual intake of antibiotics was tested in patients who were or were not known to be on antibiotic prescriptions. Using the B. subtilis (ATCC 6051) inhibitory test, the presence of antibiotics in the urine can be demonstrated specifically and at low concentrations. Of 2700 patients not known to be taking antibiotics, 8% had antibiotics in their urine. Of 400 patients with written prescriptions for antibiotics 25% had no antibiotic activity in urine. In order to avoid treatment failures, regular control of medications with the B. subtilis inhibitory test should be undertaken, especially in patients receiving oral chemotherapy.
在已知或未知正在接受抗生素处方治疗的患者中检测了抗生素的实际摄入量。使用枯草芽孢杆菌（ATCC 6051）抑制试验，可以特异性地检测到尿液中低浓度的抗生素。在2700名未知正在服用抗生素的患者中，8%的患者尿液中含有抗生素。在400名有抗生素书面处方的患者中，25%的患者尿液中没有抗生素活性。为了避免治疗失败，应定期使用枯草芽孢杆菌抑制试验对药物进行监测，尤其是在接受口服化疗的患者中。
