Geny C, Pradat P F, Yulis J, Walter S, Cesaro D, Degos J D
Department of Neurosciences, Henri Mondor Hospital, Créteil, France.
Acta Neurol Scand. 1992 Dec;86(6):632-4. doi: 10.1111/j.1600-0404.1992.tb05501.x.
Neurological exacerbation observed in MS patients is usually related to a demyelinating process. We report two patients where hypothermia (32.4 degrees C and 32.5 degrees C) and neurological exacerbation were probably due to a Wernicke encephalopathy (WE). The clinical features and the rapid efficiency of parenteral thiamine were suggestive of WE. Hypothermia is an exceptional symptom observed in MS and has been considered as resulting from hypothalamic demyelination; these two cases showed that WE which is another cause of reversible hypothermia, can be associated with MS.
在多发性硬化症（MS）患者中观察到的神经功能恶化通常与脱髓鞘过程有关。我们报告了两名患者，其体温过低（分别为32.4摄氏度和32.5摄氏度）及神经功能恶化可能是由韦尼克脑病（WE）所致。临床特征及胃肠外给予硫胺素后的快速疗效提示为韦尼克脑病。体温过低是在多发性硬化症中观察到的一种罕见症状，曾被认为是下丘脑脱髓鞘所致；这两例病例表明，作为可逆性体温过低的另一个原因的韦尼克脑病可与多发性硬化症相关联。
