从竹节虫心侧体中分离出的一种AKH/RPCH家族的色氨酸取代成员。
A tryptophan-substituted member of the AKH/RPCH family isolated from a stick insect corpus cardiacum.
作者信息
Gäde G, Kellner R, Rinehart K L, Proefke M L
机构信息
Zoology Department, University of Cape Town, Rondebosch, Republic of South Africa.
出版信息
Biochem Biophys Res Commun. 1992 Dec 30;189(3):1303-9. doi: 10.1016/0006-291x(92)90215-7.
A neuropeptide, Cam-HrTH-I, has been isolated from the corpus cardiacum of the Indian stick insect Carausius morosus. The peptide causes hyperlipaemia in Locusta migratoria and hypertrehalosaemia in Periplaneta americana and is related to the previously isolated Cam-HrTH-II (pGlu-Leu-Thr-Phe-Thr-Pro-Asn-Trp-Gly-Thr-NH2) by substitution, apparently by a hexose, on the Trp residue. This appears to be the first example of such substitution on a Trp residue.
一种神经肽，Cam-HrTH-I，已从印度竹节虫Carausius morosus的心侧体中分离出来。该肽在飞蝗Locusta migratoria中引起高脂血症，在美洲大蠊Periplaneta americana中引起高海藻糖血症，并且与先前分离的Cam-HrTH-II（pGlu-Leu-Thr-Phe-Thr-Pro-Asn-Trp-Gly-Thr-NH2）通过色氨酸残基上的取代（显然是由一个己糖取代）相关。这似乎是色氨酸残基上这种取代的首个实例。
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