人类股骨头软骨化学成分随年龄的变化
Variation of chemical composition with age in human femoral head cartilage.
作者信息
Venn M F
出版信息
Ann Rheum Dis. 1978 Apr;37(2):168-74. doi: 10.1136/ard.37.2.168.
Abstract
The chemical composition of intact femoral head cartilage was investigated with age. Full-depth cartilage showed a decrease in water content and an increase in keratan sulphate and noncollagenous material with age. When analyzed through the depth of the cartilage, keratan sulphate was shown to appear first in the deep zones and later in the surface, while water content was lost mainly in the deep zones. On a dry weight basis collagen content decreased with age. This was not a real loss but was due to a change in the proportions of other materials, mainly in the deep zones.
摘要
研究了完整股骨头软骨的化学成分随年龄的变化情况。全层软骨显示，随着年龄增长，水分含量减少，硫酸角质素和非胶原蛋白物质增加。当对软骨深度进行分析时，硫酸角质素首先出现在深层区域，随后出现在表层，而水分主要在深层区域流失。以干重计，胶原蛋白含量随年龄下降。这并非真正的减少，而是由于其他物质比例的变化，主要发生在深层区域。
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