Fösel T, Larsen R, Schwaiger C
Klinik für Anästhesiologie und Intensivmedizin, Universitätskliniken des Saarlandes, Homburg.
Anasthesiol Intensivmed Notfallmed Schmerzther. 1992 Nov;27(7):403-5. doi: 10.1055/s-2007-1000323.
11 former premature babies born at a mean gestational age of 32 weeks (range 27-34 weeks) and one baby born at term with congenital diaphragmatic hernia scheduled for inguinal hernia repair were selected to receive a spinal anaesthesia after informed written consent was obtained from one of the parents. At birth, 10 infants were intubated and received assisted ventilation; the remaining two were on nasal CPAP for 24 hours after birth. The mean post-conceptual age of the former premature infants on the day of surgery was 39 weeks (range 36-43 weeks), the mean weight was 2.2 kg (range 1.8 to 3.6 kg). One boy with congenital diaphragmatic hernia who was intubated for 19 days after birth aged 4 months on the day of operation and weighed 5.3 kg. None of the children was oxygen-dependent on the day of surgery. Spinal anaesthesia was performed in 3 children in the lateral decubitus and in 9 children in the sitting position. In each group, there was one case when spinal anaesthesia could not be performed due to a bloody spinal tap. These children received general anaesthesia, one of them in combination with a caudal block. The 9 former premature received 0.6 ml isobaric bupivacaine 0.5%, and the child born on term with diaphragmatic hernia 0.8 ml isobaric bupivacaine 0.5%. The onset of the motor blockade in the former preterm infants was within 60-90 seconds, while in the older child the onset was 10 minutes. With the given dose, the operation could be performed without any problems.(ABSTRACT TRUNCATED AT 250 WORDS)