Pedrón N, Giner J
Fertil Steril. 1978 Apr;29(4):428-30. doi: 10.1016/s0015-0282(16)43218-8.
The effect of prolactin on the glycolytic metabolism of spermatozoa from married infertile men whose semen had spermatozoal concentrations of less than 40 million/ml was studied. In a respirometry system, spermatozoa were incubated with L-U-14C-glucose as substrate. Glucose utilization and production of 14C-lactate by the spermatozoa in the presence of 100 ng of ovine prolactin were greater than in the absence of the hormone. The production of pyruvate was 2.5 times less than the production of lactate wehn spermatozoa were incubated in the absence of prolactin and 1.6 times less in the presence of prolactin. These results indicate that, in spite of having an increased glycolytic metabolism, spermatozoa from oligospermic men are are able to show additional glucose utilization in the presence of prolactin.
研究了催乳素对精液中精子浓度低于4000万/毫升的已婚不育男性精子糖酵解代谢的影响。在呼吸测定系统中，以L-U-14C-葡萄糖为底物孵育精子。在存在100纳克绵羊催乳素的情况下，精子对葡萄糖的利用和14C-乳酸的产生比不存在该激素时更多。当在不存在催乳素的情况下孵育精子时，丙酮酸的产生比乳酸的产生少2.5倍，而在存在催乳素的情况下则少1.6倍。这些结果表明，尽管少精子症男性的精子糖酵解代谢增加，但在催乳素存在的情况下，他们的精子仍能够额外利用葡萄糖。
