Frajese G, Silvestroni L, Malandrino F, Isidori A
Fertil Steril. 1976 Jan;27(1):14-20. doi: 10.1016/s0015-0282(16)41590-6.
A study has been carried out, by means of an indole microchemical technique, of the DNA content of spermatozoa from a group of 13 normal subjects and 13 patients affected by infertility, characterized by oligospermia with a clinical, hormonal, and testicular picture peculiar to "idiopathic spermatidic arrest." The DNA content of spermatozoa from the infertile, oligospermic patients was nearly double that of normal subjects. This finding can be explained tentatively on the basis of genetic and/or cytologic events occurring during meiosis.
通过吲哚微量化学技术,对一组13名正常受试者和13名不育患者的精子DNA含量进行了研究。这些不育患者的特征为少精子症,伴有“特发性精子发生停滞”所特有的临床、激素和睾丸表现。不育少精子症患者精子的DNA含量几乎是正常受试者的两倍。这一发现可根据减数分裂过程中发生的遗传和/或细胞学事件初步解释。