Stephan F K
Department of Psychology, Florida State University, Tallahassee 32306-1051.
Physiol Behav. 1992 Nov;52(5):985-95. doi: 10.1016/0031-9384(92)90381-b.
Reentrainment of anticipatory activity (AA) after phase shifts of food access was studied in rats with lesions of the suprachiasmatic nuclei. Eight- or 10-h phase delays of feeding time resulted in delaying transients of AA. Twelve-h phase shifts and some 10-h phase advances resulted in rapid reentrainment (2-3 days) without visible transients. Most phase advances of 10 h resulted in delaying transients while 8-h advances induced transients with advancing and delaying components in a number of rats. Split transients were not prevented by advancing mealtime in 1-h steps. Phase shifts of food in multiple steps failed to accelerate delay shifts but retarded advance shifts. After the first 8-h phase delay shift, increased activity reappeared at the preshift phase of AA, simultaneously with anticipation of the phase-shifted meal time. The observation of split transients indicates that two or more circadian oscillators mediate entrainment to mealtime, and the reappearance of AA at a previously established phase suggest the possibility that this system has a memory of phase displacement.
在视交叉上核受损的大鼠中研究了进食时间相位改变后预期活动（AA）的重新同步化。进食时间延迟8或10小时会导致AA的延迟性瞬变。12小时的相位改变以及一些10小时的相位提前会导致快速重新同步化（2至3天），且无明显瞬变。大多数10小时的相位提前会导致延迟性瞬变，而8小时的提前在一些大鼠中会诱导出具有提前和延迟成分的瞬变。以1小时步长提前进餐时间并不能阻止分裂瞬变。多步进食相位改变未能加速延迟性相位改变，反而减缓了提前性相位改变。在首次8小时的相位延迟改变后，AA的预移相阶段出现了活动增加，同时伴有对相移后进餐时间的预期。分裂瞬变的观察表明，两个或更多的昼夜节律振荡器介导了对进餐时间的同步化，并且AA在先前确定的相位再次出现表明该系统可能具有相位位移记忆。
