Sandvik H
Seksjon for allmennmedisin, Institutt for samfunnsmedisinske fag Universitetet i Bergen.
Tidsskr Nor Laegeforen. 1992 Dec 10;112(30):3803-5.
In 1987 there was an unexplained increase in severe streptococcal diseases in Norway and other western countries. In Norway this increase was not accompanied by a corresponding increase in acute rheumatic fever. This study investigated the occurrence of scarlet fever and acute rheumatic fever in a rural district (approximately 15,000 inhabitants) of western Norway during the years 1862-1884. Four epidemics of severe scarlet fever occurred during this period. The local doctor treated 1,155 patients (96% children), of whom 154 (13.3%) died. Acute glomerulonephritis with subsequent kidney failure seems to have been a major cause of death. During the same period 76 patients (96% adults) were treated for acute rheumatic fever. These cases were not related to the severe epidemics of scarlet fever. It is probable that different, co-circulating strains of streptococci caused the infections, which were followed by glomerulonephritis and rheumatic fever. It is possible that rheumatic fever was caused by the strain that induced the more benign "Angina tonsillaris".
1987年,挪威和其他西方国家的严重链球菌疾病出现了不明原因的增加。在挪威,这种增加并未伴随着急性风湿热的相应增加。本研究调查了1862年至1884年期间挪威西部一个农村地区(约15000名居民)猩红热和急性风湿热的发病情况。在此期间发生了四次严重猩红热疫情。当地医生治疗了1155名患者(96%为儿童),其中154人(13.3%)死亡。急性肾小球肾炎继发肾衰竭似乎是主要死因。同期有76名患者(96%为成年人)接受了急性风湿热治疗。这些病例与严重的猩红热疫情无关。很可能是不同的、共同传播的链球菌菌株引起了感染,随后导致了肾小球肾炎和风湿热。风湿热有可能是由引发较良性的“扁桃体炎”的菌株引起的。