Pärsson H, Jundzill W, Hallberg E, Norgren L
Department of Surgery and Structural Zoology, Lund University, Sweden.
Vasa. 1992;21(4):355-9.
This study evaluates the impregnation of a phenol derivative (Y105) to polymerized Dacron grafts. Y-105 has broad spectrum anti-microbial characteristics. The grafts were inserted end to side in the iliac artery of pigs. Reexploration and graft removal was performed after 7, 14 and 30 days. After pressure fixation with glutaraldehyde the grafts were evaluated for gross morphology and by scanning electron microscopy. A gradual development of pseudo-intima was observed without sign of graft occlusion. The addition of the antimicrobial impregnation did not interfere with healing.
本研究评估了一种酚类衍生物（Y105）对聚合涤纶移植物的浸渍效果。Y-105具有广谱抗菌特性。将移植物端侧吻合植入猪的髂动脉。在7天、14天和30天后进行再次探查并移除移植物。用戊二醛加压固定后，对移植物进行大体形态评估和扫描电子显微镜检查。观察到假内膜逐渐形成，且无移植物闭塞迹象。抗菌浸渍的添加并未干扰愈合过程。
