Generation of mutant mice lacking surface expression of CD4 or CD8 gene targeting.
作者信息
Mak T W, Rahemtulla A, Schilham M, Koh D R, Fung-Leung W P
机构信息
Ontario Cancer Institute, Department of Medical Biophysics, University of Toronto, Toronto, Canada.
出版信息
Adv Exp Med Biol. 1992;323:73-7. doi: 10.1007/978-1-4615-3396-2_10.
PMID:1485566
Abstract
With the use of homologous recombination in embryonic stem cells, two new strains of mice lacking surface CD4 or CD8 expression have been generated. It is hoped that they will be useful mouse strains for the study of autoimmune diseases, tissue transplantation rejections and tumour rejections.
摘要
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