Kulakov V I, Proshina I V, Kozhakhmetov A N, Sariev A K, Zherdev V P
Anesteziol Reanimatol. 1992 Jul-Aug(4):17-9.
Pharmacodynamic and pharmacokinetic peculiarities of moradol have been studied during natural delivery. It has been shown that moradol injected both intramuscularly and intravenously in the first period of labour did not inhibit the circulation in the women in labour, had no impact on the course of labour and had no negative effect on the newborn. The use of moradol is recommended for analgesia of natural delivery. A correlation has been established between blood drug concentration and its pharmacodynamic indexes in women.
在自然分娩过程中对吗多醇的药效学和药代动力学特性进行了研究。结果表明，在分娩第一阶段肌肉注射和静脉注射吗多醇均未抑制产妇的血液循环，对产程无影响，对新生儿也无不良影响。推荐使用吗多醇进行自然分娩镇痛。已在产妇中建立了血药浓度与其药效学指标之间的相关性。
