Burke T, Anderson H, Beach N, Colome S, Drew R T, Firestone M, Hauchman F S, Miller T O, Wagener D K, Zeise L
School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland.
Arch Environ Health. 1992 Nov-Dec;47(6):421-9. doi: 10.1080/00039896.1992.9938383.
Despite the development of numerous national exposure-related databases, exposure assessment remains a weak link in the chain of risk assessment and risk-management activities. Most databases include measures of environmental releases or concentrations of pollutants in specific media, but do not include actual measures of exposure. If accurate estimates of exposure experienced by populations or individuals are absent, it is impossible to judge the effectiveness of risk-management strategies. The Risk Management Work Group evaluation identified the following needs: refinement of measurements of total exposure experienced by individuals, improved characterization of the distribution of exposures in the population, longitudinal monitoring of exposure trends, and improved information about the public health implications of exposure. Recommendations are presented with the hope that the utility of existing databases will be improved and that future initiatives will be developed that meet the needs of risk management.
尽管已经建立了众多与暴露相关的国家数据库,但暴露评估仍是风险评估和风险管理活动链条中的薄弱环节。大多数数据库包含环境排放或特定介质中污染物浓度的测量数据,但不包括实际的暴露测量数据。如果缺乏对人群或个体所经历暴露的准确估计,就无法判断风险管理策略的有效性。风险管理工作组的评估确定了以下需求:完善个体所经历的总暴露测量方法,更好地描述人群中暴露分布情况,对暴露趋势进行纵向监测,以及获取更多关于暴露对公众健康影响的信息。本文提出了相关建议,希望能提高现有数据库的实用性,并推动未来能开发出满足风险管理需求的举措。