人类转酮醇酶基因的染色体定位。
Chromosomal location of the human transketolase gene.
作者信息
Lapsys N M, Layfield R, Baker E, Callen D F, Sutherland G R, Abedinia M, Nixon P F, Mattick J S
机构信息
Department of Cytogenetics and Molecular Genetics, Adelaide Children's Hospital, North Adelaide, Australia.
出版信息
Cytogenet Cell Genet. 1992;61(4):274-5. doi: 10.1159/000133421.
PMID:1486804
Abstract
The gene encoding the human transketolase enzyme (TKT) was localized by fluorescence in situ hybridization to normal and FRA3B human chromosomes. Southern blot analysis of a series of human x mouse and human x hamster hybrid cell lines confirmed this localisation. TKT maps to 3p14 and distal to FRA3B, localizing TKT to 3p14.3.
摘要
通过荧光原位杂交技术，将编码人类转酮醇酶（TKT）的基因定位到正常人和FRA3B相关的人类染色体上。对一系列人×小鼠和人×仓鼠杂交细胞系进行的Southern印迹分析证实了这一定位。TKT基因定位于3p14且在FRA3B远端，将TKT定位到3p14.3。
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