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2LD、基因计数法和单倍型分析程序:用于连锁不平衡分析的计算机程序。

2LD, GENECOUNTING and HAP: Computer programs for linkage disequilibrium analysis.

作者信息

Zhao Jing Hua

机构信息

Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London WC1E 6BT, UK.

出版信息

Bioinformatics. 2004 May 22;20(8):1325-6. doi: 10.1093/bioinformatics/bth071. Epub 2004 Feb 10.

Abstract

UNLABELLED

Computer programs are introduced which calculate pair-wise linkage disequilibrium statistics and conduct haplotype frequency estimation, including X chromosome data, and using a heuristic algorithm to handle multiple genetic markers and missing data.

AVAILABILITY

Programs 2LD, GENECOUNTING and HAP are available on Internet from http://www.hgmp.mrc.ac.uk/~jzhao and http://www.iop.kcl.ac.uk/IoP/Departments/PsychMed/GEpiBSt/software.shtml

摘要

未标注

介绍了计算机程序,这些程序可计算成对连锁不平衡统计量并进行单倍型频率估计,包括X染色体数据,且使用启发式算法处理多个遗传标记和缺失数据。

可用性

程序2LD、GENECOUNTING和HAP可从互联网上的http://www.hgmp.mrc.ac.uk/~jzhao和http://www.iop.kcl.ac.uk/IoP/Departments/PsychMed/GEpiBSt/software.shtml获取。

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