Lanktree M B, VanderBeek L, Macciardi F M, Kennedy J L
Neurogenetics Section, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, 250 College Street, Toronto M5T 1R8, Canada.
Bioinformatics. 2004 Sep 22;20(14):2315-6. doi: 10.1093/bioinformatics/bth224. Epub 2004 Apr 1.
PedSplit facilitates pedigree management for gene-gene interaction and sex specific tests for increased homogeneity within subgroups. PedSplit also provides a simple approach for calculating haplotype relative risk and generating internal 'controls'.
Executables, C++ source code and documentation for PedSplit can be downloaded from http://www.pharmacogenetics.ca in the links and software section.
PedSplit有助于进行系谱管理,以用于基因-基因相互作用研究以及针对亚组内更高同质性的性别特异性测试。PedSplit还提供了一种计算单倍型相对风险和生成内部“对照”的简单方法。
可从http://www.pharmacogenetics.ca的链接和软件部分下载PedSplit的可执行文件、C++源代码和文档。