Rolfe P
Biomedical Engineering & Medical Physics, Keele University Hospital Centre, Stoke-on-Trent, Staffs, UK.
Med Biol Eng Comput. 1992 Jul;30(4):CE29-32. doi: 10.1007/BF02446175.
The electrical and electrochemical nature of cellular components, structure and function makes it important for the possible influences by externally applied electromagnetic fields to be studied thoroughly. This is an important aspect of cellular engineering. Thermal and non-thermal influences of EM, electric and magnetic fields on biological tissues are under investigation by several groups, to improve both diagnostic and therapeutic techniques. Within the EM spectrum there is an interesting band in the infra-red, from about 700 nm to 1000 nm, where absorption by enzymes within the intracellular respiratory chain can take place. This absorption phenomenon is now used as the basis for quantitative analysis of enzyme dynamics, both in vitro and in vivo, but implications for both therapeutic and potentially damaging influences on cellular behaviour and viability also need to be considered.
细胞成分、结构和功能的电学及电化学性质,使得深入研究外部施加的电磁场可能产生的影响变得十分重要。这是细胞工程的一个重要方面。多个研究小组正在研究电磁、电场和磁场对生物组织的热效应和非热效应,以改进诊断和治疗技术。在电磁频谱中,红外区域有一个有趣的波段,大约从700纳米到1000纳米,细胞内呼吸链中的酶可以在此波段发生吸收。这种吸收现象现在被用作体外和体内酶动力学定量分析的基础,但同时也需要考虑其对细胞行为和活力的治疗及潜在损害影响。