Van der Zee P, Delpy D T
Department of Medical Physics and Bioengineering, University College Hospital, London, U.K.
Adv Exp Med Biol. 1987;215:179-91. doi: 10.1007/978-1-4684-7433-6_21.
We have been able by a Monte Carlo technique to generate the point spread function (PSF) for light in tissue for a generalized range of tissue characteristics. We have demonstrated that these can be described by an equation containing a gaussian, diffusion and exponential term. The PSF equation will allow one to estimate the limits of spatial resolution achievable with near infrared (NIR) imaging systems, and may be used in image deconvolution algorithms. Additionally an equation has been derived describing the average photon pathlength through the tissue. Finally, the light transmission and reflection (backscattering) have been illustrated as functions of scattering and absorption coefficients. These results can be used in attempting to quantify data from non-invasive NIR spectroscopy systems.
我们已经能够通过蒙特卡罗技术，针对一系列广义的组织特征生成组织中光的点扩散函数（PSF）。我们已经证明，这些函数可以用一个包含高斯、扩散和指数项的方程来描述。PSF方程将使人们能够估计近红外（NIR）成像系统可实现的空间分辨率极限，并可用于图像去卷积算法。此外，还推导了一个描述光子在组织中平均路径长度的方程。最后，光的传输和反射（后向散射）已被表示为散射和吸收系数的函数。这些结果可用于尝试对非侵入性近红外光谱系统的数据进行量化。
