Hodgson A, Evans D J, Brown M R, Gilbert P
Department of Pharmacy, University of Manchester, Great Britain.
Microbios. 1992;72(292-293):175-82.
Susceptibility of Escherichia coli to cold-shock, osmotic-shock and cold-osmotic-shock has been evaluated throughout the cellular division cycle for a variety of generation time. Two periods of sensitisation were detected. The first of these was towards cold-shock which occurred 60 min prior to cell division and might correspond to initiation of DNA replication. The second period of sensitisation was towards both cold-, osmotic- and cold-osmotic-shock and occurred immediately prior to and during cell division. Patterns and extents of sensitisation towards each of these three stresses during the second period were suggestive of a common sensitising event associated with constriction of the cell and separation.
在整个细胞分裂周期中，针对多种代时评估了大肠杆菌对冷休克、渗透休克和冷渗透休克的敏感性。检测到两个敏感时期。第一个是对冷休克敏感，发生在细胞分裂前60分钟，可能与DNA复制的起始相对应。第二个敏感时期是对冷休克、渗透休克和冷渗透休克均敏感，发生在细胞分裂前及分裂期间。在第二个时期对这三种应激中每一种的敏感模式和程度表明存在与细胞缢缩和分离相关的共同敏感事件。
