携带超广谱β-内酰胺酶的临床分离株中的氨基糖苷类修饰酶
Aminoglycoside-modifying enzymes in clinical isolates harboring extended-spectrum beta-lactamases.
作者信息
Fernandez-Rodriguez A, Canton R, Perez-Diaz J C, Martinez-Beltran J, Picazo J J, Baquero F
机构信息
Servicio de Microbiología, Hospital Clínico de San Carlos, Madrid, Spain.
出版信息
Antimicrob Agents Chemother. 1992 Nov;36(11):2536-8. doi: 10.1128/AAC.36.11.2536.
Abstract
The aminoglycoside-modifying enzymes present in the first 120 clinical isolates harboring extended-spectrum beta-lactamases isolated in Spain were studied. Most of these isolates (84%) were gentamicin resistant. The enzymes most frequently associated and cotransferred with SHV-2 or TEM-type beta-lactamases were AAC(3)V, APH(3"), and APH(3')I.
摘要
对西班牙分离出的携带超广谱β-内酰胺酶的前120株临床分离菌中存在的氨基糖苷类修饰酶进行了研究。这些分离菌中的大多数（84%）对庆大霉素耐药。与SHV-2或TEM型β-内酰胺酶最常相关并共同转移的酶是AAC(3)V、APH(3")和APH(3')I。
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