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对Pharmacia CAP系统的评估,一种用于过敏诊断(雪松花粉症)的新测试。

Evaluation of the Pharmacia CAP System, a new test for allergic diagnosis (cedar pollinosis).

作者信息

Nishikawa K, Nishikawa M, Teramoto N, Hamamoto N, Ishiguro K

机构信息

Department of Otolaryngology, Shuto General Hospital, Yamaguchi, Japan.

出版信息

Auris Nasus Larynx. 1992;19(3):169-74. doi: 10.1016/s0385-8146(12)80037-x.

DOI:10.1016/s0385-8146(12)80037-x
PMID:1489282
Abstract

For the diagnosis of allergic rhinitis we measured the specific IgE and the total serum IgE in the blood. Although we had measured them by the conventional Phadebas RAST and the Pharmacia IgE RIA before, we now adopted the new Pharmacia CAP System (CAP RAST FEIA and CAP IgE FEIA). To compare these methods, we measured the specific IgE to the cedar pollen and total serum IgE in the same blood of 224 hospital staff at the regular physical examination. As a result the new Pharmacia CAP System proved to be simpler, safer, faster, easier, more specific, and more sensitive than the Phadebas RAST and the Pharmacia IgE RIA. And also these methods correlated well with each other.

摘要

为诊断变应性鼻炎,我们检测了血液中的特异性IgE和总血清IgE。尽管我们之前曾用传统的Phadebas RAST和Pharmacia IgE RIA进行检测,但现在我们采用了新的Pharmacia CAP系统(CAP RAST FEIA和CAP IgE FEIA)。为比较这些方法,我们在224名医院工作人员定期体检时,对同一血液样本检测了针对雪松花粉的特异性IgE和总血清IgE。结果表明,新的Pharmacia CAP系统比Phadebas RAST和Pharmacia IgE RIA更简便、更安全、更快速、更易操作、更具特异性且更灵敏。而且这些方法之间相关性良好。

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