Nohara O, Imai T, Saneyoshi K, Endo T, Nagakura H, Ono M, Moriyama H
Department of Otorhinolaryngology, Jikei University School of Medicine, Japan.
Arerugi. 1996 Jun;45(6):562-9.
Titers of IgE antibody specific for the pollen of Chamaecyparis obtusa (C. obtusa) were determined by AlaSTAT and CAP-RAST in 221 patients with Japanese cedar pollinosis. IgE antibody to C. obtusa tested positive by CAP-RAST at a higher rate (80.5%) than by AlaSTAT (52.6%). The results obtained from the two assays were compared with those from intradermal skin test. CAP-RAST had a higher sensitivity than that of AlaSTAT. Because the two methods showed no differences in the determination of IgE antibody specific for Cryptomeria japonica, the above differences between AlaSTAT and CAP-RAST are surmised to be ascribable to the differences of C. obtusa antigen used in the both assays.
采用AlaSTAT和CAP-RAST检测法，测定了221例日本雪松花粉症患者针对钝叶扁柏花粉的IgE抗体效价。CAP-RAST检测法显示针对钝叶扁柏的IgE抗体阳性率（80.5%）高于AlaSTAT检测法（52.6%）。将这两种检测法的结果与皮内皮肤试验的结果进行了比较。CAP-RAST的灵敏度高于AlaSTAT。由于两种方法在测定针对日本柳杉的IgE抗体时没有差异，因此推测AlaSTAT和CAP-RAST之间的上述差异归因于两种检测法中使用的钝叶扁柏抗原的差异。
