Tuominen M, Pitkänen M, Taivainen T, Rosenberg P H
Department of Anaesthesia, Surgical Hospital, Helsinki, Finland.
Br J Anaesth. 1992 Feb;68(2):136-8. doi: 10.1093/bja/68.2.136.
We have studied in 56 patients the predictability of spread of repeated spinal anaesthesia in the same patient on the basis of a previous block. With plain 0.5% bupivacaine, prediction of the second block was accurate. A significantly higher or lower spread of analgesia than in the previous block was achieved when plain 0.5% bupivacaine was administered using a modified technique--sitting position or lower interspace, respectively. When hyperbaric 0.5% bupivacaine was injected instead of plain solution for the second block using a similar technique, no baricity-related correlation was found between the first and second blocks. Change in technique did not reduce interindividual variation in the spread of analgesia. We conclude that individual anatomical properties may play a more important role than, for example, baricity in subarachnoid distribution of a local anaesthetic solution.
我们基于之前的一次阻滞,对56例患者重复脊髓麻醉在同一患者体内的扩散可预测性进行了研究。使用单纯0.5%布比卡因时,第二次阻滞的预测是准确的。当分别采用改良技术(坐位或更低间隙)给予单纯0.5%布比卡因时,镇痛扩散范围显著高于或低于前一次阻滞。当第二次阻滞使用类似技术注射重比重0.5%布比卡因而非单纯溶液时,第一次和第二次阻滞之间未发现与比重相关的相关性。技术改变并未减少镇痛扩散的个体间差异。我们得出结论,在蛛网膜下腔局部麻醉溶液分布中,个体解剖特性可能比例如比重发挥更重要的作用。