Weber J, Diestelhorst M
Universitäts-Augenklinik, Köln, Federal Republic of Germany.
Ger J Ophthalmol. 1992;1(6):409-14.
The global mean defect (GM) is probably the most useful visual field index for glaucoma follow-up. We compared 50 regional subsets of test locations to estimate the GM. Using the data on 424 automated fields of 257 patients with either primary open-angle glaucoma or ocular hypertension, we calculated the partial sample error of the regional mean defect as compared with the GM. In many regions, the measured sample error was greater than expected for a representative sample of points. Some sample errors were up to 5 times larger (regions "upper hemifield" and "lower hemifield"). Only a few subsets proved to be representative of the whole field, namely, regions "ring 3" (10 degrees-15 degrees), "ring 4" (15 degrees-20 degrees) and "ring 5" (20 degrees-25 degrees). The use of such programs for follow-up is very accurate for staging. Moreover, theoretical calculations reveal that trend analysis is even more significant if the reduction in examination time is combined with a proportional increase in examination frequency.
总体平均缺损（GM）可能是青光眼随访中最有用的视野指标。我们比较了50个测试位置的区域子集以估算GM。利用257例原发性开角型青光眼或高眼压症患者的424个自动视野数据，我们计算了区域平均缺损与GM相比的部分样本误差。在许多区域，测量的样本误差大于代表性点样本的预期误差。一些样本误差高达预期的5倍（“上半视野”和“下半视野”区域）。只有少数子集被证明能代表整个视野，即“环3”（10度 - 15度）、“环4”（15度 - 20度）和“环5”（20度 - 25度）区域。使用此类程序进行随访对于分期非常准确。此外，理论计算表明，如果检查时间的减少与检查频率的成比例增加相结合，趋势分析会更有意义。
