Chaudhuri R K
Experientia. 1978 Jun 15;34(6):735-6. doi: 10.1007/BF01947291.
Ethylene glycol (EG) was found not to alter DNA sequences in Neurospora crassa conidia, though it is believed to be mutagenic in nature. Molecular hybridization revealed 20% increase in whole RNA transcripts in EG-treated conidia, which indicates that while untreated conidia increase RNA synthesis by 2.35fold, treated conidia are inhibited and undergo only a 1.2fold increase. Thus there is an inhibition in potential RNA synthesis, though some RNA synthesis goes on in presence of ethylene glycol.
尽管乙二醇（EG）在本质上被认为具有致突变性，但研究发现它不会改变粗糙脉孢菌分生孢子中的DNA序列。分子杂交显示，经EG处理的分生孢子中全RNA转录本增加了20%，这表明未处理的分生孢子RNA合成增加了2.35倍，而处理过的分生孢子受到抑制，仅增加了1.2倍。因此，尽管在乙二醇存在的情况下仍有一些RNA合成，但潜在的RNA合成受到了抑制。
