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Pharmacokinetics and pharmacodynamics of molsidomine in patients with liver dysfunction due to congestive heart failure.

作者信息

Huber T, Grosse-Heitmeyer W, Rietbrock S, Harder S

机构信息

Department of Cardiology, St. Bonifatius-Hospital, Lingen/Ems, Germany.

出版信息

Int J Clin Pharmacol Ther Toxicol. 1992 Nov;30(11):491-2.

PMID:1490800
Abstract
摘要

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Pharmacokinetics and pharmacodynamics of molsidomine in patients with liver dysfunction due to congestive heart failure.莫西多明在充血性心力衰竭所致肝功能不全患者中的药代动力学和药效学
Int J Clin Pharmacol Ther Toxicol. 1992 Nov;30(11):491-2.
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The role of hepatic venous congestion and endotoxaemia in the production of fulminant hepatic failure secondary to congestive heart failure.肝静脉淤血和内毒素血症在充血性心力衰竭继发暴发性肝衰竭发生中的作用。
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Pharmacokinetics of conivaptan hydrochloride, a vasopressin V(1A)/V(2)-receptor antagonist, in patients with euvolemic or hypervolemic hyponatremia and with or without congestive heart failure from a prospective, 4-day open-label study.一项为期4天的前瞻性开放标签研究,观察血管加压素V(1A)/V(2)受体拮抗剂盐酸考尼伐坦在等容性或高容性低钠血症患者中、伴或不伴有充血性心力衰竭时的药代动力学。
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引用本文的文献

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Pharmacokinetic Alterations in Patients with Chronic Heart Failure: A Systematic Review.慢性心力衰竭患者的药代动力学改变:一项系统评价。
Int J Mol Sci. 2025 Sep 28;26(19):9495. doi: 10.3390/ijms26199495.
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Clinical pharmacokinetics of drugs in patients with heart failure: an update (part 2, drugs administered orally).心力衰竭患者药物的临床药代动力学:最新进展(第2部分,口服给药)
Clin Pharmacokinet. 2014 Dec;53(12):1083-114. doi: 10.1007/s40262-014-0189-3.
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Clinical pharmacokinetics of drugs in patients with heart failure: an update (part 1, drugs administered intravenously).
心力衰竭患者药物的临床药代动力学:更新(第 1 部分,静脉内给药的药物)。
Clin Pharmacokinet. 2013 Mar;52(3):169-85. doi: 10.1007/s40262-012-0029-2.
4
Clinical pharmacokinetics of molsidomine.莫西多明的临床药代动力学
Clin Pharmacokinet. 1996 May;30(5):372-84. doi: 10.2165/00003088-199630050-00004.