Nanji A A, Greenway D C
Arch Pathol Lab Med. 1986 Jan;110(1):75-6.
We studied plasma digoxin levels by three methods in patients with congestive heart failure who had no, mild to moderate, and severe liver dysfunction secondary to the heart failure. Our results indicate that in patients with severe liver dysfunction, marked discrepancies in plasma can occur, depending on the methodology employed. The discrepancy is likely due to the presence of a digoxinlike immunoreactive substance.
我们采用三种方法研究了充血性心力衰竭患者的血浆地高辛水平，这些患者存在因心力衰竭继发的无肝功能损害、轻度至中度肝功能损害以及重度肝功能损害的情况。我们的结果表明，在重度肝功能损害患者中，根据所采用的方法不同，血浆中可能会出现显著差异。这种差异可能是由于存在一种地高辛样免疫反应性物质。
