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心脏自主控制的多种运作模式:从坎农和布鲁克斯的观点到当下的发展历程

Multiple modes of operation of cardiac autonomic control: development of the ideas from Cannon and Brooks to the present.

作者信息

Koizumi K, Kollai M

机构信息

Department of Physiology, State University of New York, Brooklyn, NY 11203.

出版信息

J Auton Nerv Syst. 1992 Nov;41(1-2):19-29. doi: 10.1016/0165-1838(92)90123-x.

DOI:10.1016/0165-1838(92)90123-x
PMID:1491113
Abstract

Since Cannon's time much emphasis has been placed on reciprocal control of the organ function by the autonomic nerves while other modes of control has been neglected. In our laboratory, prompted by Dr. Brooks, we initiated the study of the autonomic control of the heart by recording simultaneously the activity of cardiac sympathetic and parasympathetic nerves under a variety of conditions in chloralose anesthetized dogs. We have demonstrated that the central nervous system exercises reciprocal as well as non-reciprocal pattern of control over the two arms of the autonomic outflows under different physiological and behavioral conditions, and that each mode of control has an important functional significance.

摘要

自坎农时代以来,人们一直非常重视自主神经对器官功能的相互控制,而其他控制方式则被忽视了。在我们实验室,在布鲁克斯博士的推动下,我们通过在水合氯醛麻醉的狗身上,在各种条件下同时记录心脏交感神经和副交感神经的活动,启动了对心脏自主控制的研究。我们已经证明,中枢神经系统在不同的生理和行为条件下,对自主神经传出的两个分支行使相互以及非相互的控制模式,并且每种控制模式都具有重要的功能意义。

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