Hoe T S, Cheong S K, Hussin N H, Chum K W
Department of Paediatrics, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur.
Med J Malaysia. 1992 Sep;47(3):225-7.
A six year old Chinese boy with relapsed Acute Promyelocytic Leukaemia (APML) failed to respond to reinduction with Daunorubicin and Cytarabine infusion. He was successfully treated with all trans-Retinoic Acid (45 mg/m2/day) orally. After four weeks of treatment, he was in complete remission. The side effects of all trans-Retinoic Acid were negligible.
一名6岁复发性急性早幼粒细胞白血病(APML)中国男孩对柔红霉素和阿糖胞苷静脉输注再诱导治疗无反应。他口服全反式维甲酸(45毫克/平方米/天)后获得成功治疗。治疗四周后,他完全缓解。全反式维甲酸的副作用可忽略不计。