全反式维甲酸治疗早幼粒细胞白血病——一例报告
All trans-retinoic acid in the treatment of promyelocytic leukaemia--a case report.
作者信息
Hoe T S, Cheong S K, Hussin N H, Chum K W
机构信息
Department of Paediatrics, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur.
出版信息
Med J Malaysia. 1992 Sep;47(3):225-7.
PMID:1491649
Abstract
A six year old Chinese boy with relapsed Acute Promyelocytic Leukaemia (APML) failed to respond to reinduction with Daunorubicin and Cytarabine infusion. He was successfully treated with all trans-Retinoic Acid (45 mg/m2/day) orally. After four weeks of treatment, he was in complete remission. The side effects of all trans-Retinoic Acid were negligible.
摘要
一名6岁复发性急性早幼粒细胞白血病（APML）中国男孩对柔红霉素和阿糖胞苷静脉输注再诱导治疗无反应。他口服全反式维甲酸（45毫克/平方米/天）后获得成功治疗。治疗四周后，他完全缓解。全反式维甲酸的副作用可忽略不计。
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