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破伤风监测——美国,1989 - 1990年

Tetanus surveillance--United States, 1989-1990.

作者信息

Prevots R, Sutter R W, Strebel P M, Cochi S L, Hadler S

出版信息

MMWR CDC Surveill Summ. 1992 Dec 11;41(8):1-9.

PMID:1491667
Abstract

During the period 1989-1990, 117 cases of tetanus were reported from 34 states, for an average annual incidence of 0.02/100,000 population. Fifty-eight percent of patients were > or = 60 years of age, while seven (6%) were < 20 years of age, including one case of neonatal tetanus. Among adults, the risk of tetanus in those > 80 years of age was more than 10 times the risk in persons ages 20-29 years. The case-fatality rate increased with age, from 17% in persons 40-49 years of age to 50% in those > or = 80 years of age. Only 11% of patients reported having received a primary series of tetanus toxoid before disease onset, while 31% lacked a history of tetanus vaccination. Tetanus occurred following an acute injury in 78% of patients. Of patients who sought medical care, only 58% received tetanus toxoid as part of wound prophylaxis. Tetanus remains a severe disease that primarily affects unvaccinated or inadequately vaccinated older adults. Increased efforts are needed to reduce the risk of tetanus among the elderly. Health-care providers should take every opportunity to review the vaccination status of their patients and provide tetanus vaccine when indicated.

摘要

在1989年至1990年期间,34个州报告了117例破伤风病例,平均年发病率为0.02/10万人口。58%的患者年龄≥60岁,而7例(6%)年龄<20岁,其中包括1例新生儿破伤风。在成年人中,80岁以上人群患破伤风的风险是20至29岁人群的10倍以上。病死率随年龄增长而升高,40至49岁人群为17%,≥80岁人群为50%。只有11%的患者报告在发病前接受过全程破伤风类毒素接种,而31%的患者没有破伤风疫苗接种史。78%的患者破伤风发生在急性损伤之后。在寻求医疗护理的患者中,只有58%接受了破伤风类毒素作为伤口预防措施的一部分。破伤风仍然是一种严重疾病,主要影响未接种疫苗或接种不足的老年人。需要加大力度降低老年人破伤风风险。医疗保健提供者应利用一切机会检查患者的疫苗接种状况,并在有指征时提供破伤风疫苗。

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