Hori A, Walter G F, Haas J, Becker H
Institute of Neuropathology, Medizinische Hochschule Hannover, Germany.
Brain Dev. 1992 Nov;14(6):396-400. doi: 10.1016/s0387-7604(12)80347-0.
This report concerns a 24-year-old male patient with Down syndrome, complicated by a benign but true neoplastic lesion of a differentiated papilloma of the choroid plexus which simultaneously displayed a dysgenetic character. A review of the literature revealed a lack of single case reports of Down syndrome with brain tumors, which may reflect chance occurrence; however, the brain tumors in Down syndrome patients are characterized by their dysontogenetic or dysgenetic character.
本报告涉及一名24岁患有唐氏综合征的男性患者，其并发脉络丛分化型乳头状瘤的良性但真正的肿瘤性病变，同时具有发育异常的特征。文献回顾显示，缺乏唐氏综合征合并脑肿瘤的单例报告，这可能反映了偶然发生的情况；然而，唐氏综合征患者的脑肿瘤具有发育异常或发育不全的特征。
