Morales González J M, González-Montalvo J I, Del Ser Quijano T, Bermejo Pareja F
Hospital 12 de Octubre, Madrid.
Arch Neurobiol (Madr). 1992 Nov-Dec;55(6):262-6.
Although in the last decade the screening test of dementia have improved, is still being of interest the study of simple methods with a most sensitivity and specificity in the detection of the cognitive decline. Jorm et al have used recently a questionnaire (IQCODE) by which a subject's relative informs of the decline suffered by this in his cognitive capacity. In this work is showed a spanish adaptation of this test, the spanish-IQCODE, analysing it's usefulness for the detection of mild dementia. The S-IQCODE shows a diagnostic validity (sensitivity of 86%, specificity of 92%, positive predictive value of 54% and negative predictive value of 98%) greater than Mini-Mental State Examination (MMSE); it also shows a correlation with the diagnostic of dementia greater (r = 0.70 vs r = 0.37); and, different from MMSE, it doesn't show significative correlations with the age, the schooling and the premorbid intelligence. The results in this study show the S-IQCODE as a good test for the detection of the mild dementia, of greater diagnostic power than the MMSE and less contaminated than this by strange variables to the cognitive decline.
尽管在过去十年中痴呆症的筛查测试有所改进,但对在检测认知衰退方面具有更高敏感性和特异性的简单方法的研究仍备受关注。乔姆等人最近使用了一种问卷(IQCODE),通过该问卷,受试者的亲属可以告知其认知能力的衰退情况。在这项工作中展示了该测试的西班牙语改编版,即西班牙语-IQCODE,并分析了其在检测轻度痴呆症方面的实用性。西班牙语-IQCODE显示出比简易精神状态检查表(MMSE)更高的诊断效度(敏感性为86%,特异性为92%,阳性预测值为54%,阴性预测值为98%);它与痴呆症诊断的相关性也更强(r = 0.70对比r = 0.37);而且,与MMSE不同的是,它与年龄、受教育程度和病前智力没有显著相关性。本研究结果表明,西班牙语-IQCODE是检测轻度痴呆症的良好测试,其诊断能力比MMSE更强,且受认知衰退以外的其他变量影响更小。