尿中邻甲酚浓度作为胶水吸食者甲苯吸入量的指标。

Urinary ortho-cresol concentrations as an indicator of toluene inhalation in glue-sniffers.

作者信息

Yamazaki K, Tanaka E, Misawa S

机构信息

Department of Legal Medicine, St Marianna University School of Medicine, Kanagawa, Japan.

出版信息

J Forensic Sci Soc. 1992 Jul-Sep;32(3):215-23. doi: 10.1016/s0015-7368(92)73074-6.

DOI:10.1016/s0015-7368(92)73074-6

PMID:1492880

Abstract

In a Japanese study of glue-sniffers, urinary ortho-cresol and expired air toluene concentrations were determined by gas chromatography, and urinary hippuric acid concentrations by high performance liquid chromatography. There were significant differences among three sample groups (30 male "glue-sniffers", 13 "non-glue-sniffers" and 32 industrial workers) in their expired air toluene, urinary hippuric acid and ortho-cresol concentrations. Moreover, there was a better correlation between expired air toluene and urinary ortho-cresol concentrations than between toluene and urinary ortho-cresol concentrations than between toluene and hippuric acid. These results suggest that urinary ortho-cresol is a good indicator of toluene inhalation in glue-sniffers.

摘要

在一项针对日本胶水吸食者的研究中，通过气相色谱法测定尿邻甲酚和呼出气体中甲苯的浓度，通过高效液相色谱法测定尿马尿酸的浓度。在三个样本组（30名男性“胶水吸食者”、13名“非胶水吸食者”和32名产业工人）之间，他们呼出气体中的甲苯、尿马尿酸和邻甲酚浓度存在显著差异。此外，呼出气体中甲苯与尿邻甲酚浓度之间的相关性比甲苯与尿马尿酸之间的相关性更好。这些结果表明，尿邻甲酚是胶水吸食者吸入甲苯的良好指标。