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一种非抗生素抗菌混合物(C31G):C31G对阴道培养物抗菌效果的评估

A non-antibiotic antimicrobial mixture (C31G): evaluation of the antimicrobial efficiency of C31G on vaginal cultures.

作者信息

Calis S, Yulug N, Sumnu M, Ayhan A, Hincal A A

机构信息

Department of Pharmaceutical Technology, Faculty of Pharmacy, Hacettepe University, Ankara-Turkey.

出版信息

Boll Chim Farm. 1992 Oct;131(9):335-8.

PMID:1492969
Abstract

Minimum inhibitory concentrations and the effective period for cidal concentrations of an amphoteric surfactant mixture (C31G) were determined on 13 microorganisms (common bacteria, strains ATCC, and fungi) by microtiter dilution procedure. Also the antimicrobial efficiency of this composition (C31G) was evaluated on 105 culture samples which were obtained from (Turkish) patients having vaginal infections. E. coli was found to be the most frequently observed microorganism (45.45%) in these samples and C31G was determined to be active on microorganisms obtained from vagina at low concentrations in a short time.

摘要

通过微量滴定稀释法,对13种微生物(常见细菌、美国典型培养物保藏中心菌株和真菌)测定了两性表面活性剂混合物(C31G)的最低抑菌浓度和杀菌浓度的有效期。此外,还对从患有阴道感染的(土耳其)患者身上获取的105份培养样本评估了该组合物(C31G)的抗菌效果。在这些样本中,大肠杆菌是最常观察到的微生物(45.45%),并且确定C31G在短时间内对从阴道分离出的微生物在低浓度下具有活性。

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