Rhodes K E
Br J Gen Pract. 1992 Feb;42(355):68-70.
A cross-sectional survey of the prescription and monitoring of diuretic drugs for long-term use was performed in a Nottinghamshire training practice, which has 7619 patients. It was found that 330 patients were long-term users of diuretic drugs, with 79% of these patients aged 60 years or over. Twenty three different diuretic drugs were prescribed with a total cost of 13,643 pounds per year. A few drugs accounted for a disproportionate amount of the total cost, with combination diuretic drugs being particularly expensive. The most common indications for the prescription of diuretic drugs were hypertension and congestive cardiac failure. General practitioners initiated the prescribing of diuretic drugs in 87% of cases, with only a small proportion being prescribed by hospital doctors. One third of the patients had no record of urea and electrolyte levels in their notes after commencing treatment with a diuretic drug. On the basis of these findings recommendations are made for the initiation and monitoring of the long-term use of diuretic drugs.
在诺丁汉郡一家拥有7619名患者的培训诊所,开展了一项关于长期使用利尿剂药物的处方及监测情况的横断面调查。结果发现,有330名患者长期使用利尿剂药物,其中79%的患者年龄在60岁及以上。共开出了23种不同的利尿剂药物,每年总费用为13,643英镑。少数几种药物在总费用中所占比例过高,复方利尿剂药物尤其昂贵。开具利尿剂药物最常见的指征是高血压和充血性心力衰竭。87%的病例中,利尿剂药物由全科医生开出处方,只有一小部分由医院医生开出处方。三分之一的患者在开始使用利尿剂药物治疗后,病历中没有尿素和电解质水平的记录。基于这些发现,针对长期使用利尿剂药物的起始和监测提出了建议。