Williamson J, Chopin J M
Age Ageing. 1980 May;9(2):73-80. doi: 10.1093/ageing/9.2.73.
Of 1998 patients consecutively admitted to Geriatric Medicine Departments in England, Wales and Scotland in 1975--6, 81.3% were receiving prescribed drugs at time of admission. Adverse reactions were noted in 248 patients, representing 15.3% of prescribed drug takers. In 209 of these patients, it was thought that an adverse reaction had contributed to the need for admission to hospital. Full recovery from adverse reactions and sequelae occurred in 68% of those with such reactions. Hypotensive drugs, antiparkinsonian drugs and psychotropics carried the greatest risk of adverse reactions although the largest single number of adverse reactions (60) were due to diuretics which were by far the most commonly prescribed drugs (37.4% of sample).
在1975 - 1976年间，英格兰、威尔士和苏格兰的老年医学科连续收治了1998例患者，其中81.3%的患者在入院时正在接受处方药治疗。248例患者出现了不良反应，占服用处方药患者的15.3%。在这些患者中，有209例被认为不良反应是导致入院治疗的原因。出现此类反应的患者中有68%的人不良反应及后遗症完全康复。降压药、抗帕金森病药和精神药物产生不良反应的风险最大，尽管不良反应数量最多的是利尿剂（60例），而利尿剂是迄今为止最常用的药物（占样本的37.4%）。
