Torramadé J R, Hernández-Lizoain J L, Zornoza G, Pardo F, González J, Balén E, Regueira F M, Cienfuegos J A
Dpto. de Cirugía General, Clínica Universitaria de Navarra, Pamplona.
Rev Esp Enferm Dig. 1992 Dec;82(6):388-93.
We present a retrospective study of 68 esophageal cancer patients treated with surgery between 1975 and 1991. Results showed a resectability of 73.5% with the most frequent surgical approach being a Lewis esophagectomy. The mean hospitalization time was 24.7 days with a postoperative mortality of 7.3%. Other complications included anastomotic leakage, wound infection, sepsis and pulmonary disorders. Over-all survival at 3 years was 17.3%, reaching 24% in resected patients. Survival according to lymph node involvement was 13.4% for lymph node positive patients and 34.5% for node negative patients. According to histopathologic stage, survival rates were 34.6% and 8.59% for early and advanced tumor respectively, the difference being statistically significant using the Mantel-Haenszel test.
我们对1975年至1991年间接受手术治疗的68例食管癌患者进行了一项回顾性研究。结果显示,可切除率为73.5%,最常用的手术方式是Lewis食管切除术。平均住院时间为24.7天,术后死亡率为7.3%。其他并发症包括吻合口漏、伤口感染、脓毒症和肺部疾病。3年总生存率为17.3%,切除患者的生存率达到24%。根据淋巴结受累情况,淋巴结阳性患者的生存率为13.4%,淋巴结阴性患者的生存率为34.5%。根据组织病理学分期,早期肿瘤和晚期肿瘤的生存率分别为34.6%和8.59%,使用Mantel-Haenszel检验,差异具有统计学意义。