Hermanek P
Klinik und Poliklinik für Chirurgie, Universität Regensburg.
Langenbecks Arch Chir Suppl Kongressbd. 1992:95-100.
Between 1984 and 1986, 2341 patients with colorectal carcinoma from 7 German institutions entered the colorectal carcinoma study group (SGCRC). In 197 of 2053 patients with radical resections, the operation was extended by multivisceral resection. The two groups of patients were comparable in age, preoperative risk factors, postoperative morbidity, and mortality. Long-term results showed no statistically significant difference in survival according to the 5-year survival rates, calculated by the actuarial method when curative resections in UICC stage II and III were compared. After curative resection (R0), the presence or absence of intraoperative tumor-cell dissemination could be identified as a significant prognostic factor. The analysis of T4 tumors without distant metastases or serosal penetration showed a significant correlation between the percentage of patients treated by R0 resection and long-term survival in the different participating institutions.
1984年至1986年间，来自德国7家机构的2341例结直肠癌患者进入了结直肠癌研究组（SGCRC）。在2053例行根治性切除术的患者中，有197例通过多脏器切除术扩大了手术范围。两组患者在年龄、术前危险因素、术后发病率和死亡率方面具有可比性。长期结果显示，根据精算方法计算的5年生存率，在比较UICC II期和III期根治性切除术后的生存率时，两组之间无统计学显著差异。根治性切除（R0）后，术中肿瘤细胞播散的有无可被确定为一个重要的预后因素。对无远处转移或浆膜侵犯的T4肿瘤分析显示，不同参与机构中接受R0切除的患者百分比与长期生存率之间存在显著相关性。
